This workshop on granulation and tableting is a perfect combination of theory, practical demonstrations, and case-studies.
The workshop provides the basics of granulating and compacting and outlines their applications in the powder processing industry.
This workshop is an investment for those who wish to acquire knowledge of the various methods of granulation and compaction.
Typically, operators and researchers from the pharmaceucal and related industries and academia will profit from this workshop.
However, the workshop is also perfectly suitable for those who want to get a detailed overview of granulation and compaction methods in a short period of time.
08:30 Transfer from the hotel to the TTC
09:00 Reception & registration
09:30 Welcome & Introductionto TTC Stephan Rüscher, Glatt
10:00 Properties of the active compound – direct compression possible or granulation needed? Dr. Marco Schroeder, Glatt
10:45 Coffee break
11:15 Introduction to software based Formulation Strategies Niels Rottmann, BASF
12:00 Lunch break
13:15 Basics of granulation for tablet granules Dr. Kristina E. Steffens, University Bonn
14:00 Fluid bed granulation – Technology and Process Ed Godek, Glatt Air Techniques
14:45 Fluid bed granulation – the scale up approach incl. consideration of spray nozzle parameters Ed Godek, Glatt Air Techniques
15:15 Coffee break
15:45 High shear granulation and fluid bed drying. Kelly Gebman, Glatt Air Techniques
16:30 High shear granulation and fluid bed drying – the scale up approach Kelly Gebman, Glatt Air Techniques
17:00 Group Work 1: Scale up calculation for fluid bed granulation and high shear granulation processes Ed Godek, Kelly Gebman, Glatt Air Techniques
17:30 Wrap-up Day 1 Stephan Rüscher, Glatt
17:45 Tranfer to the hotel
19:00 Workshop dinner
08:00 Transfer from the hotel to the TTC
08:30 Excipients for granule and tablet formulations incl. controlled drug release concept Dr. Christian Nowak, Harke Pharma
09:15 Tableting incl. IPC considering potential trouble shooting activities Dorren Dunst, Fette Compacting
10:00 Coffee break
10:30 Impact of granule quality on the quality of resulting tablets Dr. Marco Schroeder, Glatt
11:30 PAT technologies for granulation: an overview (moisture, particle size, granule structure etc) Dr. Olivier Paquet-Durand, Glatt
12:15 Lunch break
13:30 Group Work 2: Discussion of Practical Training Program, calculation of residual moisture of granules Dr. Annette Grave, Glatt
14:00 Practical Training 1: High Shear Granulation / Fluid Bed Drying Team Innovation Center
15:30 Coffee break
16:00 Practical Training 2: Fluid Bed Granulation Team Innovation Center
17:30 Wrap-up Day 2 Stephan Rüscher, Glatt
17:45 Tranfer to the hotel or event location
19:00 Workshop dinner
08:00 Check-out from hotel and transfer to the TTC
08:30 Practical Training 3: Tableting of High Shear Granules and Fluid Bed Granules + testing of tablets (weight, hardness, friability, disintegration, etc ) Fette Compacting and SOTAX with Team Innovation Center
10:00 Coffee break
10:30 Practical Training 4: IPC testing of granules (sieve analysis, Camsizer (QC), Eyecon (offline), bulk / tap density, residual moisture (LOD), microwave etc) Team Innovation Center
12:00 Result of IPC testing and discussion of Reports Tobias Tielke SOTAX Group
12:30 Lunch break
13:45 TwinPro – an innovative granulation technology combining fluid bed and high shear technology in one. Dr. Jochen Thies, Glatt
14:30 Closing discussion: close-out, feedback on workshop: expectations fulfilled? Stephan Rüscher, Glatt
14:30 Factory tour Glatt
12:30 Transfer to Basel, German Railway Station (Badischer Bahnhof), Basel, Swiss Railway Station (SBB) and EuroAirport
Dr. Marco Schroeder Glatt GmbH, Germany
Dr. Kristina E. Steffens University of Bonn, Germany
Nils Rottmann BASF, Germany
Edward Godek Glatt Air Techniques, USA
Kelly Gebman Glatt Air Techniques, USA
Dr. Annette Grave Glatt GmbH, Germany
Dr. Christian Nowak Harke Pharma, Germany
Doreen Dunst Fette Compacting, Germany
Dr. Olivier Paquet-Durand Glatt GmbH, Germany
Tobias Tielke Sotax Group, Switzerland
Dr. Jochen Thies Glatt AG, Switzerland
Stephan Rüscher Technology Training Center, Germany